I do think playing with Simulation handling model from the start is the best way to go aside from starting on Arcade or Advanced handling then changing to Simulation afterward. It's really not that much of an adjustment to make if one were to stick with Simulation handling from the beginning. The key is getting comfortable with riding 125cc bikes with Simulation handling first then work your way up to more powerful 250cc bikes, and then the premier MotoGP bikes.
And it does seem that the teams who has the best bikes take the most Career points to unlock, but I'm not 100% sure if this is true.
Kruza